Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50002171'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002171 (3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes [3H]ADTN, a dopamine agonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002171 (3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.				J Med Chem 38: 1998-2008 (1995) BindingDB Entry DOI: 10.7270/Q2SJ1M8P
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50002171 (3-{4-[4-(4-Fluoro-phenyl)-3,6-dihydro-2H-pyridin-1...) Show SMILES Fc1ccc(cc1)C1=CCN(CCCCc2c[nH]c3ccccc23)CC1 |t:8| Show InChI InChI=1S/C23H25FN2/c24-21-10-8-18(9-11-21)19-12-15-26(16-13-19)14-4-3-5-20-17-25-23-7-2-1-6-22(20)23/h1-2,6-12,17,25H,3-5,13-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
E. Merck Darmstadt Curated by ChEMBL					Assay Description Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonist				J Med Chem 35: 4020-6 (1992) BindingDB Entry DOI: 10.7270/Q2K0736G
					More data for this Ligand-Target Pair