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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50010060'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50010060
PNG
(2-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propyl]-2H-...)
Show SMILES O=S1(=O)N(CCCN2CCN(CC2)c2ncccn2)c2cccc3cccc1c23
Show InChI InChI=1S/C21H23N5O2S/c27-29(28)19-8-2-6-17-5-1-7-18(20(17)19)26(29)12-4-11-24-13-15-25(16-14-24)21-22-9-3-10-23-21/h1-3,5-10H,4,11-16H2
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Similars
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Centre de Recherches de Vitry Alfortville Rh£ne-Poulenc Rorer

Curated by ChEMBL


Assay Description
The concentration required to inhibit [3H]spiperone binding to dopamine receptor D2 in rat brain membranes (in vitro)

J Med Chem 34: 2477-83 (1991)


BindingDB Entry DOI: 10.7270/Q2R78FT1
More data for this
Ligand-Target Pair