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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50017446'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50017446
PNG
(4-[4-(3'-Chloro-2,3,5,6-tetrahydro-[1,2']bipyrazin...)
Show SMILES Clc1nccnc1N1CCN(CCCCN2C(=O)C3C4CCC(O4)C3S2(=O)=O)CC1
Show InChI InChI=1S/C19H26ClN5O4S/c20-17-18(22-6-5-21-17)24-11-9-23(10-12-24)7-1-2-8-25-19(26)15-13-3-4-14(29-13)16(15)30(25,27)28/h5-6,13-16H,1-4,7-12H2
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Similars
PubMed
 3.30E+3n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research

Curated by ChEMBL


Assay Description
In vitro ability to inhibit [3H]spiperone binding to Dopamine receptor D2 of rat limbic structures.

J Med Chem 32: 1024-33 (1989)


BindingDB Entry DOI: 10.7270/Q21G0MVD
More data for this
Ligand-Target Pair