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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50034052'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50034052
PNG
((4-{3-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidi...)
Show SMILES COc1cc(ccc1OCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1ccccc1
Show InChI InChI=1S/C29H29FN2O4/c1-34-27-18-22(29(33)21-6-3-2-4-7-21)8-11-25(27)35-17-5-14-32-15-12-20(13-16-32)28-24-10-9-23(30)19-26(24)36-31-28/h2-4,6-11,18-20H,5,12-17H2,1H3
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n/an/a 460n/an/an/an/an/an/a



Hoechst-Roussel Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Affinity for dopamine receptor D2 binding sites by its ability to displace [3H]spiperone from rat striatum.

J Med Chem 38: 1119-31 (1995)


BindingDB Entry DOI: 10.7270/Q2S75H08
More data for this
Ligand-Target Pair