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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50051250'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50051250
PNG
(CHEMBL545144 | N-[4-(4-Benzo[d]isothiazol-3-yl-pip...)
Show SMILES COc1ccc(Br)c(OC)c1C(=O)NCCCCN1CCN(CC1)c1nsc2ccccc12
Show InChI InChI=1S/C24H29BrN4O3S/c1-31-19-10-9-18(25)22(32-2)21(19)24(30)26-11-5-6-12-28-13-15-29(16-14-28)23-17-7-3-4-8-20(17)33-27-23/h3-4,7-10H,5-6,11-16H2,1-2H3,(H,26,30)
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Similars
Article
PubMed
n/an/a 13n/an/an/an/an/an/a



Glaxo Wellcome Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against [3H]raclopride binding to dopamine receptor D2

J Med Chem 39: 1172-88 (1996)


Article DOI: 10.1021/jm950551d
BindingDB Entry DOI: 10.7270/Q2SQ912Q
More data for this
Ligand-Target Pair