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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50065579'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50065579
PNG
(4-{4-[2-(6-Fluoro-4-oxo-chroman-8-yloxy)-ethylamin...)
Show SMILES Fc1cc(OCCNCCCCc2ccc(cc2)C#N)c2OCCC(=O)c2c1
Show InChI InChI=1S/C22H23FN2O3/c23-18-13-19-20(26)8-11-28-22(19)21(14-18)27-12-10-25-9-2-1-3-16-4-6-17(15-24)7-5-16/h4-7,13-14,25H,1-3,8-12H2
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Similars
Article
PubMed
 70.4n/an/an/an/an/an/an/an/a



Yamanouchi Pharmaceutical Company, Ltd.

Curated by ChEMBL


Assay Description
Binding affinity against dopamine receptor D2 on rat striatum using [3H]-spiperone as radioligand.

J Med Chem 41: 2765-78 (1998)


Article DOI: 10.1021/jm9707840
BindingDB Entry DOI: 10.7270/Q2K073CQ
More data for this
Ligand-Target Pair