Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50109928'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50109928 (7-{[2-(4-Phenyl-piperazin-1-yl)-ethyl]-prop-2-ynyl...) Show SMILES Oc1ccc2CCC(Cc2c1)N(CCN1CCN(CC1)c1ccccc1)CC#C Show InChI InChI=1S/C25H31N3O/c1-2-12-27(24-10-8-21-9-11-25(29)20-22(21)19-24)16-13-26-14-17-28(18-15-26)23-6-4-3-5-7-23/h1,3-7,9,11,20,24,29H,8,10,12-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Tested for the binding constant against cloned human Dopamine receptor D2L in HEK cells by displacing [3H]-spiperone				Bioorg Med Chem Lett 12: 619-22 (2002) BindingDB Entry DOI: 10.7270/Q25X287P
					More data for this Ligand-Target Pair