Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50119495'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119495 (CHEMBL3613876) Show SMILES Clc1cccc(N2CCN(CCc3cn(nn3)-c3ccn4ncc(C=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H21Cl2N7O/c23-19-2-1-3-20(22(19)24)29-10-8-28(9-11-29)6-4-17-14-31(27-26-17)18-5-7-30-21(12-18)16(15-32)13-25-30/h1-3,5,7,12-15H,4,6,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119495 (CHEMBL3613876) Show SMILES Clc1cccc(N2CCN(CCc3cn(nn3)-c3ccn4ncc(C=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H21Cl2N7O/c23-19-2-1-3-20(22(19)24)29-10-8-28(9-11-29)6-4-17-14-31(27-26-17)18-5-7-30-21(12-18)16(15-32)13-25-30/h1-3,5,7,12-15H,4,6,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119495 (CHEMBL3613876) Show SMILES Clc1cccc(N2CCN(CCc3cn(nn3)-c3ccn4ncc(C=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H21Cl2N7O/c23-19-2-1-3-20(22(19)24)29-10-8-28(9-11-29)6-4-17-14-31(27-26-17)18-5-7-30-21(12-18)16(15-32)13-25-30/h1-3,5,7,12-15H,4,6,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Activity at dopamine D2S receptor (unknown origin) expressed in HEK293 cell membranes co-expressing Galpha protein subunit Galphai2 by [35S]GTPgammaS...				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119495 (CHEMBL3613876) Show SMILES Clc1cccc(N2CCN(CCc3cn(nn3)-c3ccn4ncc(C=O)c4c3)CC2)c1Cl Show InChI InChI=1S/C22H21Cl2N7O/c23-19-2-1-3-20(22(19)24)29-10-8-28(9-11-29)6-4-17-14-31(27-26-17)18-5-7-30-21(12-18)16(15-32)13-25-30/h1-3,5,7,12-15H,4,6,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Activity at dopamine D2S receptor (unknown origin) expressed in HEK293 cell membranes co-expressing Galpha protein subunit Galphao1 by [35S]GTPgammaS...				Bioorg Med Chem 23: 6195-209 (2015) Article DOI: 10.1016/j.bmc.2015.07.050 BindingDB Entry DOI: 10.7270/Q2WW7KGM
					More data for this Ligand-Target Pair