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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50421939'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50421939
PNG
(CHEMBL1744003)
Show SMILES Cc1ccc(CN2CCC3(CCCc4ccccc34)CC2)cc1
Show InChI InChI=1S/C22H27N/c1-18-8-10-19(11-9-18)17-23-15-13-22(14-16-23)12-4-6-20-5-2-3-7-21(20)22/h2-3,5,7-11H,4,6,12-17H2,1H3
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PubMed
n/an/a 174n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
In vitro for the binding affinity against dopamine receptor D2 by using [3H](-)-sulpiride as radioligand in rat striatum.

J Med Chem 35: 2033-9 (1992)


BindingDB Entry DOI: 10.7270/Q2GX4CVJ
More data for this
Ligand-Target Pair