Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50219117 (CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 0.600 | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The United States of America as Represented by the Secretary of the Department of Health and Human Services; The University of North Texas Health Science Center at Fort Worth US Patent | Assay Description Methods for performing in vitro dopamine receptor binding studies are described in Huang et al. J. Med. Chem. 44:1815-1826 (2001) and Luedtke et al. ... | US Patent US8748608 (2014) BindingDB Entry DOI: 10.7270/Q2GT5KVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50219117 (CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells | J Med Chem 50: 4135-46 (2007) Article DOI: 10.1021/jm0704200 BindingDB Entry DOI: 10.7270/Q2WW7HDW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50219117 (CHEMBL244562 | N-(4-(4-(2,3-dichlorophenyl)piperaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Antagonist activity at human dopamine D3 receptor expressed in HEK293 cells by mitogenesis assay | J Med Chem 50: 4135-46 (2007) Article DOI: 10.1021/jm0704200 BindingDB Entry DOI: 10.7270/Q2WW7HDW | |||||||||||
More data for this Ligand-Target Pair |