BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50109943'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109943 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyraz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned dopamine receptor D4 stably expressed in CHO cells by [3H]spiperone displacement.				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109943 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyraz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50109943 (3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyraz...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Tested for the effective concentration against human D4.2 receptor in CHO 10001 cells established in mitogenesis assay				Bioorg Med Chem Lett 12: 633-6 (2002) BindingDB Entry DOI: 10.7270/Q2JM2B5X
Friedrich-Alexander University Curated by ChEMBL					More data for this Ligand-Target Pair