Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 1' and Ligand = 'BDBM491481'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM491481 (US10975056, Example 464) Show SMILES CCc1c(C#N)c(SC(C(N)=O)c2ccccc2)nc(N2CCC(CC2)N2CCC[C@@H]2CO)c1C#N |r| Show InChI InChI=1S/C27H32N6O2S/c1-2-21-22(15-28)26(32-13-10-19(11-14-32)33-12-6-9-20(33)17-34)31-27(23(21)16-29)36-24(25(30)35)18-7-4-3-5-8-18/h3-5,7-8,19-20,24,34H,2,6,9-14,17H2,1H3,(H2,30,35)/t20-,24?/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<320	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Intellectual Property Development Limited; Cancer Research Technology Ltd. US Patent					Assay Description Biochemical activity of DNMT1 analyzed using SPA technology. Plates (Griener 784075) were pre-stamped with 100 nL/well of compound (11-point, 3-fold ...				US Patent US10975056 (2021) BindingDB Entry DOI: 10.7270/Q2VM4GCT
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