Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human)) | BDBM50294491 (2-amino-4-(((2S,3S,4R,5R)-3,4-dihydroxy-5-(6-(phen...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
MethylGene Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant DNMT1 expressed in baculovirus infected high five insect cells | Bioorg Med Chem Lett 19: 2747-51 (2009) Article DOI: 10.1016/j.bmcl.2009.03.113 BindingDB Entry DOI: 10.7270/Q2W37WC2 | |||||||||||
More data for this Ligand-Target Pair |