Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA (cytosine-5)-methyltransferase 3A (Homo sapiens (Human)) | BDBM50544059 (CHEMBL4171551) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
M. V. Lomonosov Moscow State University Curated by ChEMBL | Assay Description Binding affinity to DNMT3A catalytic domain (unknown origin) assessed as inhibition of enzyme-mediated DNA methylation preincubated for 1 hr followed... | Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127296 BindingDB Entry DOI: 10.7270/Q2BR8WQH | |||||||||||
More data for this Ligand-Target Pair |