Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM50510297'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50510297 (CHEMBL4577405) Show SMILES NC[C@H](Nc1nccc2ccc(cc12)-c1ccccc1Cl)c1ccccc1 |r| Show InChI InChI=1S/C23H20ClN3/c24-21-9-5-4-8-19(21)18-11-10-16-12-13-26-23(20(16)14-18)27-22(15-25)17-6-2-1-3-7-17/h1-14,22H,15,25H2,(H,26,27)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Escherichia coli his-tagged DNA gyrase supercoiling activity using pBR322 DNA in presence of ATP incubated for 1 hr by H19 dye based hi...				Bioorg Med Chem Lett 29: 1407-1412 (2019) Article DOI: 10.1016/j.bmcl.2019.03.029 BindingDB Entry DOI: 10.7270/Q2NC64HZ
					More data for this Ligand-Target Pair