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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50010354'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit B


(Mycobacterium smegmatis)		BDBM50010354
PNG
(CHEMBL3263598)
Show SMILES CCNC(=O)Nc1nc2cc(-c3cccnc3)c(NC3CCOCC3)nc2s1
Show InChI InChI=1S/C19H22N6O2S/c1-2-21-18(26)25-19-23-15-10-14(12-4-3-7-20-11-12)16(24-17(15)28-19)22-13-5-8-27-9-6-13/h3-4,7,10-11,13H,2,5-6,8-9H2,1H3,(H,22,24)(H2,21,23,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 30n/an/an/an/an/an/a



AstraZeneca India Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...

Cell Chem Biol 56: 8834-48 (2013)


Article DOI: 10.1021/jm401268f
BindingDB Entry DOI: 10.7270/Q2RV0Q7W
More data for this
Ligand-Target Pair