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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50010368'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit B


(Mycobacterium smegmatis)		BDBM50010368
PNG
(CHEMBL3263610)
Show SMILES CCNC(=O)Nc1nc2cc(-c3ccc(nc3)C#N)c(NC3CCOCC3)nc2s1
Show InChI InChI=1S/C20H21N7O2S/c1-2-22-19(28)27-20-25-16-9-15(12-3-4-14(10-21)23-11-12)17(26-18(16)30-20)24-13-5-7-29-8-6-13/h3-4,9,11,13H,2,5-8H2,1H3,(H,24,26)(H2,22,25,27,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 47n/an/an/an/an/an/a



AstraZeneca India Pvt. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...

Cell Chem Biol 56: 8834-48 (2013)


Article DOI: 10.1021/jm401268f
BindingDB Entry DOI: 10.7270/Q2RV0Q7W
More data for this
Ligand-Target Pair