Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50037087'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit B (Mycobacterium smegmatis)	BDBM50037087 (CHEMBL3355794) Show SMILES CCOC(=O)c1cc2cc(ccc2o1)N1CCN(CC1)C(=S)NCc1ccccc1 Show InChI InChI=1S/C23H25N3O3S/c1-2-28-22(27)21-15-18-14-19(8-9-20(18)29-21)25-10-12-26(13-11-25)23(30)24-16-17-6-4-3-5-7-17/h3-9,14-15H,2,10-13,16H2,1H3,(H,24,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of purified Mycobacterium smegmatis GyrB at 50 to 100 uM after 100 mins by ATPase assay				Bioorg Med Chem 22: 6552-63 (2015) Article DOI: 10.1016/j.bmc.2014.10.016 BindingDB Entry DOI: 10.7270/Q2D50PJH
					More data for this Ligand-Target Pair