Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50126826'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit B (Mycobacterium smegmatis)	BDBM50126826 (CHEMBL3628359) Show SMILES CCOC(=O)c1cnc2ccccc2c1Nc1ccc(NCCCN2CCN(CC)CC2)cc1 Show InChI InChI=1S/C27H35N5O2/c1-3-31-16-18-32(19-17-31)15-7-14-28-21-10-12-22(13-11-21)30-26-23-8-5-6-9-25(23)29-20-24(26)27(33)34-4-2/h5-6,8-13,20,28H,3-4,7,14-19H2,1-2H3,(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology&Science Curated by ChEMBL					Assay Description Inhibition of Mycobacterium smegmatis DNA gyrase B expressed in Escherichia coli BL21 (DE3) pLysS cells assessed as reduction in ATPase activity incu...				Eur J Med Chem 103: 1-16 (2015) Article DOI: 10.1016/j.ejmech.2015.06.032 BindingDB Entry DOI: 10.7270/Q2KS6TBH
					More data for this Ligand-Target Pair