Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit B (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50370232 (BA-41166E | L-5103 | RIFAMPIN | Rifadin | Rifampic...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis DNA gyrase assessed as inhibition of DNA supercoiling after 30 mins by electrophoresis | Bioorg Med Chem 24: 877-85 (2016) Article DOI: 10.1016/j.bmc.2016.01.011 BindingDB Entry DOI: 10.7270/Q2MP5682 | |||||||||||
More data for this Ligand-Target Pair |