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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50378421'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit B


(Streptococcus pneumoniae)		BDBM50378421
PNG
(CHEMBL578149)
Show SMILES CCCn1ccc(cc1=O)-c1cc(-c2ncc(C)cn2)n2cc(NC(=O)NCC)nc2c1
Show InChI InChI=1S/C23H25N7O2/c1-4-7-29-8-6-16(11-21(29)31)17-9-18(22-25-12-15(3)13-26-22)30-14-19(27-20(30)10-17)28-23(32)24-5-2/h6,8-14H,4-5,7H2,1-3H3,(H2,24,28,32)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 97n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of Streptococcus pneumoniae SP-3 gyrB by enzyme coupled phosphate assay

Bioorg Med Chem Lett 19: 5302-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.141
BindingDB Entry DOI: 10.7270/Q23X87KD
More data for this
Ligand-Target Pair