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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit B' and Ligand = 'BDBM50499013'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA gyrase subunit B


(Staphylococcus aureus)		BDBM50499013
PNG
(CHEMBL3736371)
Show SMILES CCNC(=O)Nc1cn(Cc2ccccc2)c2cc(cnc12)-c1cccnc1
Show InChI InChI=1S/C22H21N5O/c1-2-24-22(28)26-19-15-27(14-16-7-4-3-5-8-16)20-11-18(13-25-21(19)20)17-9-6-10-23-12-17/h3-13,15H,2,14H2,1H3,(H2,24,26,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.20E+3n/an/an/an/an/an/a



Cubist Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of Staphylococcus aureus DNA GyraseB ATPase activity using linear pBR322 DNA as substrate incubated for 30 mins by fluorescence polarizati...

J Med Chem 58: 8503-12 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00961
BindingDB Entry DOI: 10.7270/Q24B34BK
More data for this
Ligand-Target Pair