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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA ligase' and Ligand = 'BDBM22986'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA ligase


(Bacteriophage T4)		BDBM22986
PNG
(18-[6-(piperidin-1-yl)hexyl]-8-thia-18-azatetracyc...)
Show SMILES C(CCCn1c-2c(CCSc3ccccc-23)c2ccccc12)CCN1CCCCC1
Show InChI InChI=1S/C27H34N2S/c1(8-17-28-18-9-3-10-19-28)2-11-20-29-25-14-6-4-12-22(25)23-16-21-30-26-15-7-5-13-24(26)27(23)29/h4-7,12-15H,1-3,8-11,16-21H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.04E+5n/an/an/an/a7.625



India Central Drug Research Institute



Assay Description
The assay was performed using a 40-bp double-stranded DNA substrate carrying a single-strand nick between bases 22 and 23. The reaction products were...

Proteins 69: 97-111 (2007)


Article DOI: 10.1002/prot.21457
BindingDB Entry DOI: 10.7270/Q2P55KSS
More data for this
Ligand-Target Pair