Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase beta' and Ligand = 'BDBM50260079'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase beta (Rattus norvegicus)	BDBM50260079 (30-(4'-hydroxybenzoyloxy)-11alpha-hydroxylupane-20...) Show SMILES C[C@]12CC[C@H]([C@@H]1[C@H]1C[C@@H](O)[C@@H]3[C@@]4(C)CCC(=O)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2)C(=C)COC(=O)c1ccc(O)cc1 |r| Show InChI InChI=1S/C37H52O5/c1-22(21-42-32(41)23-8-10-24(38)11-9-23)25-12-15-34(4)18-19-36(6)26(30(25)34)20-27(39)31-35(5)16-14-29(40)33(2,3)28(35)13-17-37(31,36)7/h8-11,25-28,30-31,38-39H,1,12-21H2,2-7H3/t25-,26+,27+,28-,30+,31+,34+,35-,36+,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Virginia Curated by ChEMBL					Assay Description Inhibition of lyase activity of rat DNA polymerase beta after 30 mins by deoxyribose phosphate excision assay				J Nat Prod 67: 1744-7 (2004) Article DOI: 10.1021/np040057p BindingDB Entry DOI: 10.7270/Q2251K28
					More data for this Ligand-Target Pair