Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase catalytic subunit' and Ligand = 'BDBM222914'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) )	BDBM222914 (US9315499, 4056) Show SMILES CC1CN(C1)C(=O)Cn1c2ncc(OCC3(CC3)C#N)cc2cc(C(=O)NCc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C27H26ClN5O4/c1-17-12-32(13-17)23(34)14-33-24-19(8-21(11-30-24)37-16-27(15-29)6-7-27)9-22(26(33)36)25(35)31-10-18-2-4-20(28)5-3-18/h2-5,8-9,11,17H,6-7,10,12-14,16H2,1H3,(H,31,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair