Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase lambda' and Ligand = 'BDBM50198198'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase lambda (Homo sapiens (Human))	BDBM50198198 (CHEMBL3889506) Show SMILES [#6]\[#6](-[#6])=[#6]/[#6]-[#6][C@@]1([#6])[#6@H](-[#6]\[#6]=[#6](/[#6])-[#6]\[#6]=[#6]\C([#6])([#6])[#8])-[#6][C@@]2([#6]\[#6]=[#6](/[#6])-[#6])[#6](-[#8])=[#6](-[#6](=O)-c3ccc(-[#8])c(-[#8])c3)-[#6](=O)[C@]1([#6]\[#6]=[#6](/[#6])-[#6])[#6]2=O |r,t:28,TLB:49:48:20.8.6:29.27.40| Show InChI InChI=1S/C43H58O7/c1-27(2)13-11-22-41(10)32(17-15-30(7)14-12-21-40(8,9)50)26-42(23-19-28(3)4)37(47)35(36(46)31-16-18-33(44)34(45)25-31)38(48)43(41,39(42)49)24-20-29(5)6/h12-13,15-16,18-21,25,32,44-45,47,50H,11,14,17,22-24,26H2,1-10H3/b21-12+,30-15+/t32-,41+,42+,43-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kobe Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged DNA polymerase lambda assessed as reduction in [3H]dTTP incorporation using poly(dA)/oligo(dT)18 as templa...				J Nat Prod 79: 1798-807 (2016) Article DOI: 10.1021/acs.jnatprod.6b00255 BindingDB Entry DOI: 10.7270/Q2930W5F
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