Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 1 (Homo sapiens (Human)) | BDBM50045359 ((20RS)-Amino-acetic acid 10-amino-4-ethyl-3,13-dio...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of Topoisomerase I by cleavage complex formation in human HL-60 cells | J Med Chem 36: 2689-700 (1993) BindingDB Entry DOI: 10.7270/Q2KP82RH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 1 (Homo sapiens (Human)) | BDBM50045359 ((20RS)-Amino-acetic acid 10-amino-4-ethyl-3,13-dio...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description Inhibition of Topoisomerase I by cleavage complex formation in intact human HL-60 cells | J Med Chem 36: 2689-700 (1993) BindingDB Entry DOI: 10.7270/Q2KP82RH | |||||||||||
More data for this Ligand-Target Pair |