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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50080280'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Homo sapiens (Human))		BDBM50080280
PNG
(2-(1-Hydroxy-ethyl)-5,8-dimethoxy-[1,4]naphthoquin...)
Show SMILES COc1ccc(OC)c2c(O)c(cc(O)c12)C(C)=O
Show InChI InChI=1S/C14H14O5/c1-7(15)8-6-9(16)12-10(18-2)4-5-11(19-3)13(12)14(8)17/h4-6,16-17H,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.50E+6n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Compound was evaluated for the inhibition of DNA topoisomerase-I of calf thymus

Bioorg Med Chem Lett 9: 2407-12 (1999)


BindingDB Entry DOI: 10.7270/Q2TH8KVH
More data for this
Ligand-Target Pair