Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 1 (Homo sapiens (Human)) | BDBM50083606 (1-hydroxy-6-(2-hydroxy-1-hydroxymethylethylamino)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 650 | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of Topoisomerase I-mediated DNA cleavage using supercoiled pBR322 plasmid DNA. | Bioorg Med Chem Lett 9: 3307-12 (2000) BindingDB Entry DOI: 10.7270/Q2KD1X4C | |||||||||||
More data for this Ligand-Target Pair |