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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 1' and Ligand = 'BDBM50496609'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 1


(Yersinia pestis)		BDBM50496609
PNG
(CHEMBL3134418)
Show SMILES CCCCCc1cc(OC(=O)c2ccc(O)cc2O)cc(O)c1C(O)=O
Show InChI InChI=1S/C19H20O7/c1-2-3-4-5-11-8-13(10-16(22)17(11)18(23)24)26-19(25)14-7-6-12(20)9-15(14)21/h6-10,20-22H,2-5H2,1H3,(H,23,24)
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.00E+5n/an/an/an/an/an/a



University of Hawai'i at Hilo

Curated by ChEMBL


Assay Description
Inhibition of Yersinia pestis topoisomerase 1-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis

Medchemcomm 4: (2013)


Article DOI: 10.1039/C3MD00238A
BindingDB Entry DOI: 10.7270/Q23F4SM4
More data for this
Ligand-Target Pair