Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha' and Ligand = 'BDBM50147401'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM50147401 (2'-Phenyl-[2,4']bibenzooxazolyl | CHEMBL113081) Show SMILES c1ccc(cc1)-c1nc2c(cccc2o1)-c1nc2ccccc2o1 Show InChI InChI=1S/C20H12N2O2/c1-2-7-13(8-3-1)19-22-18-14(9-6-12-17(18)24-19)20-21-15-10-4-5-11-16(15)23-20/h1-12H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibitory concentration against human DNA topoisomerase II, alpha mediated relaxation of pBR322; no measurable activity				Bioorg Med Chem Lett 14: 3221-6 (2004) Article DOI: 10.1016/j.bmcl.2004.03.095 BindingDB Entry DOI: 10.7270/Q24T6HTC
					More data for this Ligand-Target Pair