BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha' and Ligand = 'BDBM50496617'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50496617
PNG
(CHEMBL3134419)
Show SMILES CCCCCc1cc(O)cc(O)c1C(=O)Oc1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C19H20O7/c1-2-3-4-5-11-8-12(20)9-16(22)17(11)19(25)26-13-6-7-14(18(23)24)15(21)10-13/h6-10,20-22H,2-5H2,1H3,(H,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.25E+5n/an/an/an/an/an/a



University of Hawai'i at Hilo

Curated by ChEMBL


Assay Description
Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled plasmid DNA by agarose gel electrophoresis

Medchemcomm 4: (2013)


Article DOI: 10.1039/C3MD00238A
BindingDB Entry DOI: 10.7270/Q23F4SM4
More data for this
Ligand-Target Pair