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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 3' and Ligand = 'BDBM50022145'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 3


(Bacillus subtilis)		BDBM50022145
PNG
(6-Benzylamino-5-ethyl-1H-pyrimidine-2,4-dione | CH...)
Show SMILES CCc1c(NCc2ccccc2)[nH]c(=O)[nH]c1=O
Show InChI InChI=1S/C13H15N3O2/c1-2-10-11(15-13(18)16-12(10)17)14-8-9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H3,14,15,16,17,18)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 2.82E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Concentration producing 50% inhibition of Bacillus subtilis DNA topoisomerase III in the absence of dGTP using DNA Polymerase assay

J Med Chem 29: 676-81 (1986)


BindingDB Entry DOI: 10.7270/Q2MP528D
More data for this
Ligand-Target Pair