Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit A' and Ligand = 'BDBM50178882'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 4 subunit A (Staphylococcus aureus)	BDBM50178882 (9-cyclopropyl-6-fluoro-7-(2-methylpyridin-3-yl)iso...) Show SMILES Cc1ncccc1-c1cc2n(C3CC3)c3s[nH]c(=O)c3c(=O)c2cc1F Show InChI InChI=1S/C19H14FN3O2S/c1-9-11(3-2-6-21-9)12-8-15-13(7-14(12)20)17(24)16-18(25)22-26-19(16)23(15)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,22,25)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Staphylococcus aureus ATCC 29213 wild type Topo 4				Bioorg Med Chem Lett 16: 1277-81 (2006) Article DOI: 10.1016/j.bmcl.2005.11.064 BindingDB Entry DOI: 10.7270/Q26D5SKN
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