Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 4 subunit A' and Ligand = 'BDBM50178903'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 4 subunit A (Staphylococcus aureus)	BDBM50178903 (9-cyclopropyl-6-fluoro-7-(isoquinolin-5-yl)isothia...) Show SMILES Fc1cc2c(cc1-c1cccc3cnccc13)n(C1CC1)c1s[nH]c(=O)c1c2=O Show InChI InChI=1S/C22H14FN3O2S/c23-17-8-16-18(9-15(17)14-3-1-2-11-10-24-7-6-13(11)14)26(12-4-5-12)22-19(20(16)27)21(28)25-29-22/h1-3,6-10,12H,4-5H2,(H,25,28)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Achillion Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Staphylococcus aureus ATCC 29213 wild type Topo 4				Bioorg Med Chem Lett 16: 1277-81 (2006) Article DOI: 10.1016/j.bmcl.2005.11.064 BindingDB Entry DOI: 10.7270/Q26D5SKN
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