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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase I subunit RPA1' and Ligand = 'BDBM50582334'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-directed RNA polymerase I subunit RPA1


(Homo sapiens (Human))
BDBM50582334
PNG
(CHEMBL5093028)
Show SMILES O=C(NCC1CCCN1)c1cccn2c1nc1cc3ccccc3cc1c2=O
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 780n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay


Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00660
BindingDB Entry DOI: 10.7270/Q2KW5KXW
More data for this
Ligand-Target Pair