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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA-directed RNA polymerase subunit beta' and Ligand = 'BDBM50137479'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA-directed RNA polymerase subunit beta


(Escherichia coli)
BDBM50137479
PNG
(1-Cyclohexyl-2-phenyl-1H-benzoimidazole-5-carboxyl...)
Show SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccccc1
Show InChI InChI=1S/C20H20N2O2/c23-20(24)15-11-12-18-17(13-15)21-19(14-7-3-1-4-8-14)22(18)16-9-5-2-6-10-16/h1,3-4,7-8,11-13,16H,2,5-6,9-10H2,(H,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against calf thymus RNA polymerase


Bioorg Med Chem Lett 14: 119-24 (2003)


BindingDB Entry DOI: 10.7270/Q21J9968
More data for this
Ligand-Target Pair