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Found 1 hit Enz. Inhib. hit(s) with Target = 'Decaprenylphosphoryl-beta-D-ribose oxidase' and Ligand = 'BDBM50517957'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Decaprenylphosphoryl-beta-D-ribose oxidase


(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)		BDBM50517957
PNG
(CHEMBL4437244)
Show SMILES Cc1c(CCC(=O)N2CCCC2)c(=O)n2c3ccccc3[nH]c2c1C#N
Show InChI InChI=1S/C20H20N4O2/c1-13-14(8-9-18(25)23-10-4-5-11-23)20(26)24-17-7-3-2-6-16(17)22-19(24)15(13)12-21/h2-3,6-7,22H,4-5,8-11H2,1H3
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 70n/an/an/an/an/an/a



The Maharaja Sayajirao University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis H37Rv DprE1 using FPR as substrate preincubated for 6.5 hrs followed by substrate addition by resazurin dye-...

J Med Chem 61: 8563-8593 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00281
BindingDB Entry DOI: 10.7270/Q2PR80CC
More data for this
Ligand-Target Pair