Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM176295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM176295 (US9688696, 10) Show SMILES Clc1cccc(Cl)c1NC(=O)N1CCN(CC1)c1ccc(cc1)-c1ccn(Cc2ccccc2)n1 Show InChI InChI=1S/C27H25Cl2N5O/c28-23-7-4-8-24(29)26(23)30-27(35)33-17-15-32(16-18-33)22-11-9-21(10-12-22)25-13-14-34(31-25)19-20-5-2-1-3-6-20/h1-14H,15-19H2,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	316	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
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