Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM176344'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM176344 (US9688696, 60) Show SMILES Clc1cc(CN2CCCC2)cc(Cl)c1NC(=O)N1CCN(CC1)c1ccc(cc1)-c1ncn(CCc2ccccc2)n1 Show InChI InChI=1S/C32H35Cl2N7O/c33-28-20-25(22-38-13-4-5-14-38)21-29(34)30(28)36-32(42)40-18-16-39(17-19-40)27-10-8-26(9-11-27)31-35-23-41(37-31)15-12-24-6-2-1-3-7-24/h1-3,6-11,20-21,23H,4-5,12-19,22H2,(H,36,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	98	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
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