Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM176351'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM176351 (US9688696, 67) Show SMILES CC(C)n1ncc2nc([nH]c12)-c1ccc(cc1)N1CCN(CC1)C(=O)Nc1ccccc1Cl Show InChI InChI=1S/C24H26ClN7O/c1-16(2)32-23-21(15-26-32)27-22(29-23)17-7-9-18(10-8-17)30-11-13-31(14-12-30)24(33)28-20-6-4-3-5-19(20)25/h3-10,15-16H,11-14H2,1-2H3,(H,27,29)(H,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	7.4	25
Janssen Pharmaceutica N.V. US Patent					Assay Description DGAT activity in membrane preparations was assayed in 50 mM Tris-HCl (pH 7.4), 150 mM MgCl2, 1 mM EDTA and 0.2% BSA, containing 50 μM DAG, 32 &#...				US Patent US9688696 (2017) BindingDB Entry DOI: 10.7270/Q24X55ZP
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