Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM220930'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220930 (US9302996, 45) Show SMILES CC(C)(COc1ccc(cn1)-c1ccc(-c2ncc([nH]2)C2(CC2)C(F)(F)F)c(F)c1)C(O)=O Show InChI InChI=1S/C23H21F4N3O3/c1-21(2,20(31)32)12-33-18-6-4-14(10-28-18)13-3-5-15(16(24)9-13)19-29-11-17(30-19)22(7-8-22)23(25,26)27/h3-6,9-11H,7-8,12H2,1-2H3,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
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