Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM220939'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220939 (US9302996, 54-4) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1ccc(-c2ncc([nH]2)C2(CC2)C(F)(F)F)c(F)c1 Show InChI InChI=1S/C24H23F4N3O3/c1-13-8-19(34-12-22(2,3)21(32)33)29-10-16(13)14-4-5-15(17(25)9-14)20-30-11-18(31-20)23(6-7-23)24(26,27)28/h4-5,8-11H,6-7,12H2,1-3H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
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