Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM220944'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220944 (US9302996, 59) Show SMILES CC(C)Cc1cnc([nH]1)-c1ccc(nc1)-c1ccc(OCC(C)(C)C(O)=O)nc1 Show InChI InChI=1S/C22H26N4O3/c1-14(2)9-17-12-25-20(26-17)16-5-7-18(23-11-16)15-6-8-19(24-10-15)29-13-22(3,4)21(27)28/h5-8,10-12,14H,9,13H2,1-4H3,(H,25,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
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