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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM351919'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1


(Homo sapiens (Human))		BDBM351919
PNG
(US9796729, 3)
Show SMILES Nc1ncnc2OCCN(c3ccc4n(ccc4c3)C3CCC3)C(=O)c12
Show InChI InChI=1S/C19H19N5O2/c20-17-16-18(22-11-21-17)26-9-8-24(19(16)25)14-4-5-15-12(10-14)6-7-23(15)13-2-1-3-13/h4-7,10-11,13H,1-3,8-9H2,(H2,20,21,22)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 14.7n/an/an/an/an/an/a



GLAXOSMITHKLINE LLC

US Patent


Assay Description
For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...

US Patent US9796729 (2017)


BindingDB Entry DOI: 10.7270/Q2057J2H
More data for this
Ligand-Target Pair