Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50020049'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50020049 (CHEMBL3287884) Show SMILES CCCCCCCNC(=O)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1 |r,wU:26.28,wD:29.32,(3.09,-11.07,;4.44,-11.81,;4.46,-13.35,;5.81,-14.1,;7.12,-13.31,;7.1,-11.77,;5.74,-11.03,;5.71,-9.5,;7.03,-8.7,;8.37,-9.43,;6.99,-7.16,;5.64,-6.41,;5.6,-4.87,;6.91,-4.07,;8.27,-4.81,;9.58,-4.01,;10.93,-4.75,;10.97,-6.3,;9.66,-7.1,;8.3,-6.36,;12.25,-3.95,;12.21,-2.41,;13.53,-1.61,;14.88,-2.35,;14.92,-3.89,;13.6,-4.7,;16.19,-1.55,;16.16,-.01,;17.47,.8,;18.83,.06,;20.14,.86,;20.1,2.4,;21.42,3.2,;18.75,3.14,;18.86,-1.49,;17.55,-2.29,)| Show InChI InChI=1S/C30H40N2O4/c1-2-3-4-5-6-17-31-30(35)32-18-19-36-28-21-26(15-16-27(28)32)25-13-11-24(12-14-25)23-9-7-22(8-10-23)20-29(33)34/h11-16,21-23H,2-10,17-20H2,1H3,(H,31,35)(H,33,34)/t22-,23-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50020049 (CHEMBL3287884) Show SMILES CCCCCCCNC(=O)N1CCOc2cc(ccc12)-c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1 |r,wU:26.28,wD:29.32,(3.09,-11.07,;4.44,-11.81,;4.46,-13.35,;5.81,-14.1,;7.12,-13.31,;7.1,-11.77,;5.74,-11.03,;5.71,-9.5,;7.03,-8.7,;8.37,-9.43,;6.99,-7.16,;5.64,-6.41,;5.6,-4.87,;6.91,-4.07,;8.27,-4.81,;9.58,-4.01,;10.93,-4.75,;10.97,-6.3,;9.66,-7.1,;8.3,-6.36,;12.25,-3.95,;12.21,-2.41,;13.53,-1.61,;14.88,-2.35,;14.92,-3.89,;13.6,-4.7,;16.19,-1.55,;16.16,-.01,;17.47,.8,;18.83,.06,;20.14,.86,;20.1,2.4,;21.42,3.2,;18.75,3.14,;18.86,-1.49,;17.55,-2.29,)| Show InChI InChI=1S/C30H40N2O4/c1-2-3-4-5-6-17-31-30(35)32-18-19-36-28-21-26(15-16-27(28)32)25-13-11-24(12-14-25)23-9-7-22(8-10-23)20-29(33)34/h11-16,21-23H,2-10,17-20H2,1H3,(H,31,35)(H,33,34)/t22-,23-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting an...				ACS Med Chem Lett 5: 544-9 (2014) Article DOI: 10.1021/ml400527n BindingDB Entry DOI: 10.7270/Q2KS6T3C
					More data for this Ligand-Target Pair