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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50328364'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1


(Homo sapiens (Human))		BDBM50328364
PNG
(CHEMBL1257208 | cis-diethyl 2-(2,6-dimethylmorphol...)
Show SMILES CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(cc(nn12)N1C[C@H](C)O[C@H](C)C1)-c1ccccc1 |r|
Show InChI InChI=1S/C28H35N3O5/c1-6-12-22-24(27(32)34-7-2)25(28(33)35-8-3)26-21(20-13-10-9-11-14-20)15-23(29-31(22)26)30-16-18(4)36-19(5)17-30/h9-11,13-15,18-19H,6-8,12,16-17H2,1-5H3/t18-,19+
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PC cid
PC sid
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Similars
Article
PubMed
n/an/a>3.00E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs

Bioorg Med Chem Lett 20: 6030-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.066
BindingDB Entry DOI: 10.7270/Q2RV0NX1
More data for this
Ligand-Target Pair