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Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50328368'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1


(Homo sapiens (Human))		BDBM50328368
PNG
(CHEMBL1257442 | diethyl 2-(dimethylamino)-4-phenyl...)
Show SMILES CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(cc(nn12)N(C)C)-c1ccccc1
Show InChI InChI=1S/C24H29N3O4/c1-6-12-18-20(23(28)30-7-2)21(24(29)31-8-3)22-17(16-13-10-9-11-14-16)15-19(26(4)5)25-27(18)22/h9-11,13-15H,6-8,12H2,1-5H3
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Article
PubMed
n/an/a 830n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs

Bioorg Med Chem Lett 20: 6030-3 (2010)


Article DOI: 10.1016/j.bmcl.2010.08.066
BindingDB Entry DOI: 10.7270/Q2RV0NX1
More data for this
Ligand-Target Pair