Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50380048'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50380048 (CHEMBL2012629) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)C(=O)Nc1nnc(Cc2ccccc2F)s1 |r,wU:7.10,wD:4.3,(42.15,-8.67,;40.61,-8.69,;39.86,-10.04,;39.82,-7.37,;38.28,-7.39,;37.49,-6.06,;35.96,-6.08,;35.21,-7.43,;35.99,-8.75,;37.52,-8.74,;33.67,-7.45,;32.89,-6.13,;31.35,-6.15,;30.6,-7.49,;31.38,-8.8,;32.92,-8.79,;29.06,-7.5,;28.28,-6.18,;28.31,-8.84,;26.77,-8.86,;25.85,-7.63,;24.39,-8.12,;24.4,-9.66,;23.06,-10.41,;21.74,-9.63,;21.76,-8.09,;20.43,-7.31,;19.09,-8.06,;19.08,-9.61,;20.4,-10.39,;20.39,-11.93,;25.87,-10.12,)| Show InChI InChI=1S/C24H24FN3O3S/c25-20-4-2-1-3-19(20)14-21-27-28-24(32-21)26-23(31)18-11-9-17(10-12-18)16-7-5-15(6-8-16)13-22(29)30/h1-4,9-12,15-16H,5-8,13-14H2,(H,29,30)(H,26,28,31)/t15-,16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 in Chang cells using [14C]-glycerol as substrate assessed as decrease in triglycerides synthesis after 6 hrs by...				Bioorg Med Chem Lett 22: 2497-502 (2012) Article DOI: 10.1016/j.bmcl.2012.02.006 BindingDB Entry DOI: 10.7270/Q2VQ33PZ
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50380048 (CHEMBL2012629) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)C(=O)Nc1nnc(Cc2ccccc2F)s1 |r,wU:7.10,wD:4.3,(42.15,-8.67,;40.61,-8.69,;39.86,-10.04,;39.82,-7.37,;38.28,-7.39,;37.49,-6.06,;35.96,-6.08,;35.21,-7.43,;35.99,-8.75,;37.52,-8.74,;33.67,-7.45,;32.89,-6.13,;31.35,-6.15,;30.6,-7.49,;31.38,-8.8,;32.92,-8.79,;29.06,-7.5,;28.28,-6.18,;28.31,-8.84,;26.77,-8.86,;25.85,-7.63,;24.39,-8.12,;24.4,-9.66,;23.06,-10.41,;21.74,-9.63,;21.76,-8.09,;20.43,-7.31,;19.09,-8.06,;19.08,-9.61,;20.4,-10.39,;20.39,-11.93,;25.87,-10.12,)| Show InChI InChI=1S/C24H24FN3O3S/c25-20-4-2-1-3-19(20)14-21-27-28-24(32-21)26-23(31)18-11-9-17(10-12-18)16-7-5-15(6-8-16)13-22(29)30/h1-4,9-12,15-16H,5-8,13-14H2,(H,29,30)(H,26,28,31)/t15-,16-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in baculovirus infected Sf9 cells after 60 mins by scintillation counting method				Bioorg Med Chem Lett 22: 2497-502 (2012) Article DOI: 10.1016/j.bmcl.2012.02.006 BindingDB Entry DOI: 10.7270/Q2VQ33PZ
					More data for this Ligand-Target Pair