Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50399682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50399682 (CHEMBL2178946) Show SMILES Cc1nc(C)c(nc1C(N)=O)-c1ccc([C@@H]2CC[C@H](CC(O)=O)CC2)c(Cl)c1 |r,wU:15.15,18.19,(2.81,-20.05,;4.14,-19.28,;5.48,-20.05,;6.81,-19.28,;8.14,-20.05,;6.81,-17.74,;5.47,-16.97,;4.14,-17.74,;2.81,-16.97,;1.47,-17.73,;2.81,-15.43,;8.14,-16.98,;8.14,-15.43,;9.47,-14.66,;10.8,-15.42,;12.14,-14.65,;13.47,-15.42,;14.8,-14.65,;14.8,-13.11,;16.14,-12.34,;17.47,-13.11,;18.8,-12.34,;17.47,-14.65,;13.47,-12.34,;12.13,-13.12,;10.81,-16.97,;12.14,-17.74,;9.47,-17.75,)| Show InChI InChI=1S/C21H24ClN3O3/c1-11-19(25-20(21(23)28)12(2)24-11)15-7-8-16(17(22)10-15)14-5-3-13(4-6-14)9-18(26)27/h7-8,10,13-14H,3-6,9H2,1-2H3,(H2,23,28)(H,26,27)/t13-,14+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant DGAT1 expressed in Sf9 cells by liquid scintillography				J Med Chem 55: 10610-29 (2012) Article DOI: 10.1021/jm301296t BindingDB Entry DOI: 10.7270/Q2XD12T3
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